ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex - Concepedia

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ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex

DOI Full Paper Access

38

Citations

44

References

2014

Year

Qiao Zhang, Zhe Yang, Zhuqing Jia, Cuiling Liu, Guo Chen, Huafei Lü, Ping Chen, Kangtao Ma, Weiping Wang, Chunyan Zhou

Molecular Cancer

Abstract

Our results provide the first evidence that ISL-1 is tightly linked to NHL proliferation and development by promoting c-Myc transcription, and its aberrant expression was regulated by p-STAT3/p-c-Jun/ISL-1 complex activation.

References

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