Concepedia

Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 as monotherapy in patients with hypercholesterolaemia (MENDEL): a randomised, double-blind, placebo-controlled, phase 2 study

Michael J. Koren, Robert C. Scott, Jae B. Kim, Beat Knüsel, Thomas Liu, Lei Lei, Michael A. Bolognese, Scott M. Wasserman

The Lancet · 2012 · 362 citations · 21 references

DOI

Concepts

References

21

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report

Circulation · 2002 · 14.1K citations

, , +15

Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)

Scott M. Grundy, Diane M. Becker, Luther T. Clark et al. · Civil War Book Review · 2002 · 12.2K citations

, , +12

ESC/EAS Guidelines for the management of dyslipidaemias: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)

Željko Reiner, Alberico L. Catapano, Guy De Backer et al. · European Heart Journal · 2011 · 3.5K citations · Full text

, , +17

Sequence Variations in <i>PCSK9,</i> Low LDL, and Protection against Coronary Heart Disease

Jonathan C. Cohen, Eric Boerwinkle, Thomas H. Mosley et al. · New England Journal of Medicine · 2006 · 3.2K citations · Full text

, , +17

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

Marianne Abifadel, Mathilde Varret, Jean‐Pierre Rabès et al. · Nature Genetics · 2003 · 3K citations

, , +10