A Mitochondrial Target Sequence Polymorphism in Manganese Superoxide Dismutase Predicts Inferior Survival in Breast Cancer Patients Treated with Cyclophosphamide - Concepedia

Concepedia

Publication | Open Access

A Mitochondrial Target Sequence Polymorphism in Manganese Superoxide Dismutase Predicts Inferior Survival in Breast Cancer Patients Treated with Cyclophosphamide

DOI Full Paper Access

44

Citations

43

References

2009

Year

Sharon A. Glynn, Brenda J. Boersma, Tiffany M. Howe, Hege Edvardsen, Stephanie Geisler, Julie E. Goodman, Lisa A. Ridnour, Per Eystein Lønning, Anne‐Lise Børresen‐Dale, Bjørn Naume,

Clinical Cancer Research

Abstract

The Val16Ala polymorphism affects survival of patients receiving cyclophosphamide-containing chemotherapy. The findings provide the first evidence pointing toward a mechanism for cyclophosphamide resistance in breast cancer patients.

References

	Year	Citations

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