Glucose monitoring using electromagnetic waves and microsensor with interdigitated electrodes

Abstract

A microscale glucose sensor for biomedical applications was fabricated utilizing the enzyme glucose oxidase and the polymer poly(o-phenylenediamine). A solution containing the enzyme immobilized in the polymer was deposited on interdigitated microelectrodes to form sensor arrays. This was achieved using novel nanopatterning technology offered by BioForce NanoeNablertrade. Samples containing different concentrations of glucose were applied to the sensor while the system was being monitored for variances in either current or conductance. The resulting changes in the electrical characteristics of the sensor monitored in real time were found to be proportional to the different concentrations of glucose applied. It is strongly believed that the size reduction of the sensor to a few microns described in this paper creates new opportunities in the areas of chemical and biological sensor development.