Functionalized Nanocompartments (Synthosomes) with a Reduction‐Triggered Release System

Abstract

An open and shut case: The developed synthosomes are a subclass of polymersomes with a block-copolymer membrane and a modified embedded transmembrane channel protein (FhuA Δ1–160; see top view of model), which acts as a selective gate. The first reduction-triggered and sterically controlled release system for transmembrane control of the chemical fluxes has been developed by chemically labeling lysine residues in the channel of FhuA Δ1–160.