Prophylaxis of Irinotecan-Induced Diarrhea with Neomycin and Potential Role for <b> <i>UGT1A1*28</i> </b> Genotype Screening: A Double-Blind, Randomized, Placebo-Controlled Study - Concepedia

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Prophylaxis of Irinotecan-Induced Diarrhea with Neomycin and Potential Role for <b> <i>UGT1A1*28</i> </b> Genotype Screening: A Double-Blind, Randomized, Placebo-Controlled Study

DOI Full Paper Access

88

Citations

47

References

2006

Year

Floris A. de Jong, Diederik F.S. Kehrer, Ron H.J. Mathijssen, Geert‐Jan Creemers, Peter de Bruijn, Ron H. N. van Schaik, André Planting, Ate van der Gaast, Ferry A.L.M. Eskens, J Janssen,

Abstract

Our results do not suggest a major role for neomycin as prophylaxis for irinotecan-induced delayed-type diarrhea. It is suggested that the UGT1A1*28 genotype status could be used as a screening tool for a priori prevention of irinotecan-induced delayed-type diarrhea.

References

	Year	Citations

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