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Heterocycles of biological importance. Part 5. The formation of novel biologically active pyrimido[1,2-a]benzimidazoles from allenic nitriles and aminobenzimidazoles

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References

2001

Year

Abstract

The reaction of allenic nitriles with 2-aminobenzimidazoles gives 2-aminopyrimido[1,2-a]benzimidazoles 5 in very good yields. The pharmacological screening of compound 5a, 5d and 5i shows that they possess slight antibiotic and antiarrythmic properties.