Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells

Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent

Bey-Dih Chang, Mari E. Swift, Mei Shen et al. · Proceedings of the National Academy of Sciences · 2001 · 305 citations · Full text

Medicine, Cancer Biology, Oncology +17

Elevation of Mitochondrial Transmembrane Potential and Reactive Oxygen Intermediate Levels Are Early Events and Occur Independently from Activation of Caspases in Fas Signaling

Katalin Bánki, Eliza Hutter, Nick J. Gonchoroff et al. · The Journal of Immunology · 1999 · 272 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis

Kirsteen H. Maclean, Frank C. Dorsey, John L. Cleveland et al. · Journal of Clinical Investigation · 2007 · 270 citations · Full text

Life Sciences, Cell Biology, Oncology +15

Noxa Up-regulation and Mcl-1 Cleavage Are Associated to Apoptosis Induction by Bortezomib in Multiple Myeloma

Patricia Gomez‐Bougie, Soraya Wuillème‐Toumi, Emmanuelle Ménoret et al. · Cancer Research · 2007 · 237 citations · Full text

Medicine, Oncology, Pharmacology +17

Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation

Vitaliy O. Kaminskyy, Tatiana S. Piskunova, I. B. Zborovskaya et al. · Autophagy · 2012 · 163 citations · Full text

Life Sciences, Cell Biology, Oncology +17