Concepedia

Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells

Robert W. Robey, Tomasz Obrzut, Suneet Shukla, Orsolya Polgár, Sira Macalou, Julian Bahr, Attilio Di Pietro, Suresh V. Ambudkar, Susan E. Bates

Cancer Chemotherapy and Pharmacology · 2009 · 25 citations · 32 references

DOI

Concepts

References

32

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.8K citations

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MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models

François‐Xavier Mahon, Françis Belloc, Valérie Lagarde et al. · Blood · 2003 · 538 citations · Full text

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C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance.

Yasuo Imai, Minoru Nakane, Kumie Kage et al. · PubMed · 2002 · 441 citations

, , +17

Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity

Robert W. Robey, Yasuyuki Honjo, K Morisaki et al. · British Journal of Cancer · 2003 · 371 citations · Full text

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Pheophorbide a Is a Specific Probe for ABCG2 Function and Inhibition

Robert W. Robey, Kenneth Steadman, Orsolya Polgár et al. · Cancer Research · 2004 · 355 citations · Full text

, , +17