Concepedia

Amplified detection of protein cancer biomarkers using DNAzyme functionalized nanoprobes

Wenhui Zhou, Zhu Chun-ling, Chunhua Lü, Xiuchun Guo, Farong Chen, Huanghao Yang, Xiaoru Wang

Chemical Communications · 2009 · 54 citations · 20 references

DOI

Concepts

Abstract

The high sensitive immunoassay of protein cancer biomarkers is achieved by using of peroxidase-mimicking DNAzyme heavily functionalized gold nanoparticles as catalytic probe.

References

20

Selective Colorimetric Detection of Polynucleotides Based on the Distance-Dependent Optical Properties of Gold Nanoparticles

Robert Elghanian, James J. Storhoff, Robert C. Mucic et al. · Science · 1997 · 4.4K citations

, , +17

Nanoparticle-Based Bio-Bar Codes for the Ultrasensitive Detection of Proteins

Jin‐Min Nam, C. Shad Thaxton, Chad A. Mirkin · Science · 2003 · 2.4K citations

, , +17

DNA-enhanced peroxidase activity of a DNA aptamer-hemin complex

Paola Travascio, Yingfu Li, Dipankar Sen · Chemistry & Biology · 1998 · 1K citations · Full text

, , +12

Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease

D.G. Georganopoulou, Lei Chang, Jwa‐Min Nam et al. · Proceedings of the National Academy of Sciences · 2005 · 840 citations · Full text

, , +17

Biomedical and clinical applications of immunoassays and immunosensors for tumor markers

Jie Wu, Zhifeng Fu, Feng Yan et al. · TrAC Trends in Analytical Chemistry · 2007 · 458 citations

, , +14