Solvent Extraction and Ion Exchange · 2014 · 63 citations · 18 references
Natural SciencesNuclear EngineeringNuclear MedicineDiagnostic Nuclear MedicineNuclear ChemistryTherapeutic Nuclear MedicineNuclear Medicine ChemistryNuclear Medicine PhysicsRadiation ChemistryRadioactive DecayRadiochemical AnalysisRadiopharmaceuticalsAnalytical SeparationsRadioisotope Separation ChemistryRadionuclide AnalysisRadionuclide IdentificationRadionuclide PurificationRadionuclide Purity AssessmentRadionuclide SeparationThorium Chemistry
A method of isolation of actinium-225 for nuclear medical applications from thorium targets irradiated by protons is presented. It comprises liquid extraction and extraction chromatography separations. The method demonstrates high (> 85%) chemical yield and radionuclide purity of the final product. An impurity of 227Ac (0.1% at the end of bombardment) does not hinder 225Ac from being used for medical 225Ac/213Bi generators.
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Tumor Therapy with Targeted Atomic Nanogenerators
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Design and synthesis of 225Ac radioimmunopharmaceuticals
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