Solvent Extraction and Ion Exchange · 2014 · 60 citations · 18 references
EngineeringMedium-energy ProtonsNuclear Medical ApplicationsMedicine-applicable Actinium-225Extraction Chromatography SeparationsRadioactive ContaminationThorium TargetsRadiopharmaceutical TherapyRadioanalytical ChemistryAnalytical ChemistryProton TherapyRadiation ApplicationChemistryRadiation ChemistryRadiation OncologyNuclear MedicineChromatographyRadioactive Waste Disposal
A method of isolation of actinium-225 for nuclear medical applications from thorium targets irradiated by protons is presented. It comprises liquid extraction and extraction chromatography separations. The method demonstrates high (> 85%) chemical yield and radionuclide purity of the final product. An impurity of 227Ac (0.1% at the end of bombardment) does not hinder 225Ac from being used for medical 225Ac/213Bi generators.
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Tumor Therapy with Targeted Atomic Nanogenerators
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