Biodegradable Poly-D,L-Lactic Acid-Polyethylene Glycol Block Copolymers as a BMP Delivery System for Inducing Bone

Abstract

New synthetic biodegradable delivery systems will play an important role in the clinical applications of rhBMPs in which local formation of bone via an osteoinductive graft material is needed. Further pre-clinical and clinical work is necessary to establish the safety of these implants before they are adopted for widespread clinical use.