A Concise, Modular Synthesis of Chiral Peraza-Macrocycles Using Chiral Aziridines

Abstract

[reaction: see text] Novel chiral peraza-macrocycles were synthesized from chiral aziridines as a common building block. Efficient syntheses of chiral [26]-N(6), [12]-N(4), [9]-N(3), and [14]-N(4) systems were accomplished.