Water: The Ideal Hydrogen‐Atom Source in Free‐Radical Chemistry Mediated by Ti^III and Other Single‐Electron‐Transfer Metals?

Abstract

Hydrogen-atom transfer from water to free radicals can be mediated by aqua complexes of titanium(III) (see scheme). Asymmetric epoxidation in combination with [Cp2TiCl]/H2O-mediated reductive epoxide opening can be viewed as an alternative with complementary stereoselectivity to the hydroboration–epoxidation method for the enantioselective synthesis of anti-Markovnikov alcohols from alkenes. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z600831_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.