Preclinical Efficacy of the c-Met Inhibitor CE-355621 in a U87 MG Mouse Xenograft Model Evaluated by<sup>18</sup>F-FDG Small-Animal PET - Concepedia

Concepedia

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Preclinical Efficacy of the c-Met Inhibitor CE-355621 in a U87 MG Mouse Xenograft Model Evaluated by<sup>18</sup>F-FDG Small-Animal PET

DOI Full Paper Access

60

Citations

25

References

2007

Year

Jeffrey R. Tseng, Keon Wook Kang, Mangal Dandekar, Shahriar Yaghoubi, Joseph H. Lee, James G. Christensen, Stephen Muir, Patrick W. Vincent, Neil R. Michaud, Sanjiv S. Gambhir

Journal of Nuclear Medicine

Abstract

CE-355621 is an efficacious novel antineoplastic chemotherapeutic agent that inhibits (18)F-FDG accumulation earlier than tumor volume changes in a mouse xenograft model. These results support the use of (18)F-FDG PET to assess early tumor response for CE-355621.

References

	Year	Citations

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