Kupffer cell depletion by CI₂MDP‐liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy

Abstract

We conclude that KCs are important for hepatocyte regeneration after PH. Delayed liver regeneration in KC-depleted rats can be explained, at least in part, by an imbalanced hepatic cytokine expression, thereby suppressing important growth-stimulating cytokines.