Twofold Unsymmetrical CH Functionalization of PyrDipSi‐Substituted Arenes: A General Method for the Synthesis of Substituted <i>meta</i>‐Halophenols

Abstract

And the world is your oyster…︁ Sequential halogenation/oxygenation reactions of 2-diisopropylsilylpyrimidine-substituted arenes provide a general and efficient synthesis of substituted meta-halophenols from simple aryl iodides (see scheme; Piv=pivaloyl). The products are poised to undergo diverse CC, CN, and CO bond-forming reactions that enable the transformation of their framework and the introduction of valuable functionalities. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.