Rel/NF-κB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors

High-efficiency transformation of mammalian cells by plasmid DNA.

C Chen, Hiroto Okayama · Molecular and Cellular Biology · 1987 · 5.3K citations · Full text

Calcium Phosphate Precipitation, Medicine, Natural Sciences +15

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

Liang Peng, Arthur B. Pardee · Science · 1992 · 5K citations

Genetics, Oligonucleotide Primers, Molecular Biology +21

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

Manfred Gossen, Heidelberg Bujard · Proceedings of the National Academy of Sciences · 1992 · 4.9K citations

Viral Replication, Molecular Regulation, Immunology +20

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Leif W. Ellisen, Jeffrey Bird, Daniel C. West et al. · Cell · 1991 · 1.7K citations

Chromatin, Cell Lineage, Developmental Biology +9

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Eric H. Schroeter, Jeffrey A. Kisslinger, Raphael Kopan · Nature · 1998 · 1.6K citations

Signal Transduction, Signaling Pathway, Cell Interaction +6