Colloidal Crystal Beads as Supports for Biomolecular Screening

Abstract

Crystal balls: Colloidal crystal microbeads with a three-dimensional photonic crystal structure can be fabricated with a droplet generator and their reflection spectra used as encoding elements. A multiplex bioassay demonstrates their reliability as encoded carriers (see picture: red, green, and blue beads are immobilized with human, mouse, and rabbit immunoglobulin, respectively).