Effect of chronic apocynin treatment on nitric oxide and reactive oxygen species production in borderline and spontaneous hypertension

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

Joseph S. Beckman, ThomasJ Beckman, Jake Y. Chen et al. · Proceedings of the National Academy of Sciences · 1990 · 7.1K citations

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Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

David S. Bredt, Solomon H. Snyder · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

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Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

Sanjay Rajagopalan, Stephan Kurz, Thomas Münzel et al. · Journal of Clinical Investigation · 1996 · 2.4K citations · Full text

Life Sciences, Pharmacology, Physiology +16

NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium

K. M. Mohazzab, Pawel M. Kaminski, Michael S. Wolin · American Journal of Physiology-Heart and Circulatory Physiology · 1994 · 535 citations

Life Sciences, Biochemistry, Cell Biology +17

Antioxidant Effects of Vitamins C and E Are Associated With Altered Activation of Vascular NADPH Oxidase and Superoxide Dismutase in Stroke-Prone SHR

Xin Chen, Rhian M. Touyz, Jeong Bae Park et al. · Hypertension · 2001 · 409 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17