Concepedia

A negative correlation between insulin-like peptide 3 and bisphenol A in human cord blood suggests an effect of endocrine disruptors on testicular descent during fetal development

Nicolas Chevalier, Françoise Brücker-Davis, N. Lahlou, Patrick Coquillard, M. Pugeat, Peggy Pacini, Patricia Panaïa‐Ferrari, K. Wagner-Mahler, Patrick Fénichel

Human Reproduction · 2014 · 62 citations · 46 references

DOIFull text

Open access

Abstract

The negative correlation between cb free BPA and INSL3 provides indirect evidence for an impact of EEDs on human fetal Leydig cell INSL3 production and points to cbINSL3 as a possible target of EED action during fetal testis development.

References

46

Molecular Pharmacology

L L Iversen · Nature New Biology · 1971 · 812 citations

Cryptorchidism in mice mutant for Insl3

Serge Nef, Luis F. Parada · Nature Genetics · 1999 · 737 citations

, , +6

Parent bisphenol A accumulation in the human maternal-fetal-placental unit.

Gilbert Schönfelder, W. Wittfoht, Hartmut Hopp et al. · Environmental Health Perspectives · 2002 · 697 citations · Full text

, , +24

Targeted Disruption of the Insl3 Gene Causes Bilateral Cryptorchidism

Stephan Zimmermann, Gerd Steding, Judith M. A. Emmen et al. · Molecular Endocrinology · 1999 · 678 citations · Full text

New metabolites of di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium-labelled DEHP

Holger M. Koch, Hermann M. Bolt, Ralf Preuss et al. · Archives of Toxicology · 2005 · 533 citations

, , +5