“On Water”‐Promoted Direct Coupling of Indoles with 1,4‐Benzoquinones without Catalyst

Abstract

Abstract A highly efficient direct coupling of indole compounds with 1,4‐benzoquinones was developed “on water” in the absence of any catalyst, organic co‐solvent, or additives. The “on‐water” conditions provided the best yields of the corresponding products and the only system to produce bis(coupling) products. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)