Concepedia

Isatinones A and B, New Antifungal Oxindole Alkaloids from Isatis costata

Itrat Fatima, Ijaz Ahmad, Itrat Anis, Abdul Malik, Nighat Afza

Molecules · 2007 · 44 citations · 5 references

DOIFull text

Open access

Concepts

Abstract

Two new oxindole alkaloids isatinone A (1) and B (2) have been isolated from Isatis costata, along with the known trisindoline. Their structures have been assigned on the basis of spectroscopic techniques and chemical studies. Both new compounds showed significant antifungal activity.

References

5

Marine Natural Products. XXXIV. Trisindoline, a New Antibiotic Indole Trimer, Produced by a Bacterium of Vibrio sp. Separated from the Marine Sponge Hyrtios altum.

Shunji Aoki, Katsuhiko Gato, K. Matsunami et al. · Chemical and Pharmaceutical Bulletin · 1994 · 206 citations · Full text

, , +16

A Tandem Heck-Carbocyclization/Suzuki-Coupling Approach to the Stereoselective Syntheses of Asymmetric 3,3-(Diarylmethylene)indolinones

Wing S. Cheung, Raymond J. Patch, Mark R. Player · The Journal of Organic Chemistry · 2005 · 127 citations

, , +14

Antifungal steroidal lactones from Withania coagulance

M. Iqbal Choudhary, Dur-e-Shahwar, Zeba Parveen et al. · Phytochemistry · 1995 · 124 citations

, , +4

New Indole Derivatives with Free Radical Scavenging Activity from <i>Agrocybe cylindracea</i>

Won‐Gon Kim, In‐Kyoung Lee, Jong-Pyung Kim et al. · Journal of Natural Products · 1997 · 47 citations

, , +17

Enzyme Inhibition Studies of Oxindole Alkaloids from Isatis costata

Abdul Malik, Itrat Fatima, Ijaz Ahmad et al. · Heterocycles · 2006 · 19 citations · Full text

, , +11