Asian Journal of Research in Chemistry · 2008 · 12 citations · 1 references
PharmacyChemistryMedicinal ChemistryDrug DesignDrug DiscoveryOrganic ChemistryLead Compound DesignNatural Product-based Drug DesignAldehydesAntibiotic DiscoveryAntimicrobial Drug DevelopmentAntimicrobial MetabolitesNovel Antibacterial AgentsNovel Antibacterial Drug Discovery
Some novel chalcones were synthesized by condensation of N-(4-phenylthiazol-2-yl) acetamide with aromatic aldehydes in presence of aqueous potassium hydroxide solution at room temperature. All the title compounds characterized on the basis of their IR, 1H NMR spectroscopic data and elemental analysis. All the compounds have been screened for antimicrobial activity by the cup-plate method.
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