A Comparative Study of Goblet Cell and Pancreatic Exocine Autoantibodies Combined with ASCA and pANCA in Chinese and Caucasian Patients with IBD

Abstract

This study identified that GAB was not useful in our patients with IBD. PAB expression was highly specific for CD and more sensitive in Chinese than Caucasian patients with CD. The combination of PAB, pANCA, and ASCA testing improved the differentiation between UC and CD, particularly in isolated colonic disease, compared with pANCA and ASCA testing alone.