Bioinformatics · 2003 · 6.2K citations · 13 references
Life SciencesBioinformaticsGeneticsMolecular EvolutionPopulation GeneticsStatistical GeneticsDna SequencingGenetic Diversity AssessmentCoalescent-based InferenceDifferentiationDna Sequence Data AnalysisGene Flow AssessmentGene Flow DynamicsPolymorphism-based TestsSingle-nucleotide Polymorphism Analysis
SUMMARY: DnaSP is a software package for the analysis of DNA polymorphism data. Present version introduces several new modules and features which, among other options allow: (1) handling big data sets (approximately 5 Mb per sequence); (2) conducting a large number of coalescent-based tests by Monte Carlo computer simulations; (3) extensive analyses of the genetic differentiation and gene flow among populations; (4) analysing the evolutionary pattern of preferred and unpreferred codons; (5) generating graphical outputs for an easy visualization of results. AVAILABILITY: The software package, including complete documentation and examples, is freely available to academic users from: http://www.ub.es/dnasp
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Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.
Fumio Tajima · Genetics · 1989 · 14.2K citations · Full text
Life Sciences, Biology, Genetics +13
Statistical tests of neutrality of mutations.
Yun Fu, Wen‐Hsiung Li · Genetics · 1993 · 4.1K citations · Full text