BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis <i>In Vitro</i> and Shows Antitumor Activity <i>In Vivo</i> in Hematologic Malignancies - Concepedia

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BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis <i>In Vitro</i> and Shows Antitumor Activity <i>In Vivo</i> in Hematologic Malignancies

207

Citations

34

References

2012

Year

Michelle Kuhne, Tanya Mulvey, Blake Belanger, Sharline Chen, Chin Pan, Colin Chong, Fei Cao, Wafa Niekro, Tom Kempe, Karla A. Henning,

Clinical Cancer Research

Abstract

BMS-936564/MDX-1338 is a potent CXCR4 antagonist which is efficacious as monotherapy in tumor-bearing mice and is currently in phase I for the treatment of relapsed/refractory AML, NHL, CLL, and multiple myeloma.

References

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