Concepedia

Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial

Jianping Weng, Yanbing Li, Wen Xu, Lixin Shi, Qiao Zhang, Dalong Zhu, Yun Hu, Zhiguang Zhou, Xiang Yan, Haoming Tian,

The Lancet · 2008 · 769 citations · 14 references

DOI

Concepts

References

14

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

David R. Matthews, J P Hosker, A. Rudenski et al. · Diabetologia · 1985 · 31.4K citations · Full text

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

The Lancet · 1998 · 20.1K citations

, , +13

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)

The Lancet · 1998 · 8.3K citations

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Insulin Inhibits Intranuclear Nuclear Factor κB and Stimulates IκB in Mononuclear Cells in Obese Subjects: Evidence for an Anti-inflammatory Effect?

Paresh Dandona, Ahmad Aljada, Priya Mohanty et al. · The Journal of Clinical Endocrinology & Metabolism · 2001 · 667 citations

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Mechanism of Metformin Action in Obese and Lean Noninsulin-Dependent Diabetic Subjects*

Ralph A. DeFronzo, Nir Barzilai, Donald C. Simonson · The Journal of Clinical Endocrinology & Metabolism · 1991 · 411 citations

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