Concepedia

Immunoblotting detection of gamma-catenin (plakoglobin) antibody in the serum of a patient with paraneoplastic pemphigus

M Ishii, Junko Izumi, Hiroshi Fujiwara, Masaaki Ito, Minoru HAMADA

British Journal of Dermatology · 2001 · 14 citations · 14 references

DOI

Concepts

Abstract

We report a patient with paraneoplastic pemphigus associated with a thymic tumour. Immunoblot study using affinity-purified gamma-catenin protein revealed that his serum recognized gamma-catenin (plakoglobin) in epidermal, thymic tumour and mouse bladder extracts.

References

14

Paraneoplastic Pemphigus

Grant J. Anhalt, SooChan Kim, John R. Stanley et al. · New England Journal of Medicine · 1990 · 1K citations · Full text

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Immunoglobulin-Gene Rearrangements as Unique Clonal Markers in Human Lymphoid Neoplasms

Andrew Arnold, Jeffrey Cossman, Ajay Bakhshi et al. · New England Journal of Medicine · 1983 · 610 citations

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Plakoglobin: A protein common to different kinds of intercellular adhering junctions

Pamela Cowin, Hans‐Peter KAPPRELL, Werner W. Franke et al. · Cell · 1986 · 506 citations

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Antibodies against desmoglein 3 (pemphigus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice.

Masayuki Amagai, T. Níshikaẃa, Hossein C. Nousari et al. · Journal of Clinical Investigation · 1998 · 316 citations · Full text

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T-Cell Receptor Gene Rearrangements as Clinical Markers of Human T-Cell Lymphomas

Virginia Bertness, Ilan R. Kirsch, Gregory Hollis et al. · New England Journal of Medicine · 1985 · 251 citations

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