Concepedia

<i>rpoB</i> Mutation Conferring Rifampin Resistance in <i>Streptococcus pyogenes</i>

H. Aubry‐Damon, Marc Galimand, G Gerbaud, Patrice Courvalin

Antimicrobial Agents and Chemotherapy · 2002 · 31 citations · 12 references

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Abstract

Streptococcus pyogenes BM4478 and Staphylococcus aureus BM4479 were isolated from a patient undergoing rifampin therapy. High-level resistance to rifampin was due to the following mutations in the rpoB gene: Ser522Leu in strain BM4478 and His526Asn and Ser574Leu in strain BM4479.

References

12

Mapping and sequencing of mutations in the Escherichia colirpoB gene that lead to rifampicin resistance

Ding Jun Jin, Carol A. Gross · Journal of Molecular Biology · 1988 · 696 citations

, , +12

Rifampin: Mechanisms of Action and Resistance

W. Wehrli · Clinical Infectious Diseases · 1983 · 402 citations

, , +16

Characterization of Mutations in the<i>rpoB</i>Gene That Confer Rifampin Resistance in<i>Staphylococcus aureus</i>

H. Aubry‐Damon, Claude–James Soussy, Patrice Courvalin · Antimicrobial Agents and Chemotherapy · 1998 · 226 citations · Full text

, , +15

Rifampicin region revisited. New rifampicin-resistant and streptolydigin-resistant mutants in the beta subunit of Escherichia coli RNA polymerase

K. Severinov, Maria Soushko, A Goldfarb et al. · Journal of Biological Chemistry · 1993 · 204 citations · Full text

, , +14

Marker Discrimination in Transformation and Mutation of Pneumococcus

Jean-Gérard Tiraby, Mark A. Fox · Proceedings of the National Academy of Sciences · 1973 · 170 citations · Full text

, , +12