Depressive-like behavioral alterations and c-fos expression in the dopaminergic brain regions in WAG/Rij rats with genetic absence epilepsy

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

Social Sciences, Behavioral Sciences, Psychology +9

Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum.

Ann M. Graybiel, Rosario Moratalla, H.A. Robertson · Proceedings of the National Academy of Sciences · 1990 · 962 citations

Medicine, Neuroscience, Pharmacology +17

The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs

Sandra E. File · Journal of Neuroscience Methods · 1980 · 818 citations

Medicine, Pharmacology, Behavioral Pharmacology +5

OPEN‐FIELD BEHAVIOR IN THE RAT: WHAT DOES IT MEAN?*

Victor H. Denenberg · Annals of the New York Academy of Sciences · 1969 · 581 citations

Life Sciences, Behavioral Sciences, Zoology +11

Exploration of mice in a black and white test box: Validation as a model of anxiety

B. Costall, Brian J. Jones, M.E. Kelly et al. · Pharmacology Biochemistry and Behavior · 1989 · 542 citations

Social Sciences, Behavioral Sciences, Psychology +11