Neural Correlates of Emotional Distractibility in Bipolar Disorder Patients, Unaffected Relatives, and Individuals With Hypomanic Personality

Abstract

The results suggest that emotional dysregulation leads to exacerbated neuropsychological deficits in bipolar patients, as evidenced by behavioral slowing and task-related hyperactivation. The lack of such a deficit in high-risk populations suggests that it occurs only after disease onset, rather than representing a vulnerability marker.