Publication | Open Access
GC-Content Evolution in Mammalian Genomes: The Biased Gene Conversion Hypothesis
481
Citations
47
References
2001
Year
DnaGeneticsGenomic MechanismMolecular BiologyMolecular GeneticsGenomicsGenomic FragmentsGene StructureGenome AnalysisGenome StructureDna ReplicationGene EvolutionGc-content EvolutionBioinformaticsBiologyChromatinBase CompositionNatural SciencesEvolutionary BiologyGenetic MechanismMedicineMammalian Genomes
BASE composition is spatially structured in mammalian genomes. From sodium chloride centrifugation experiments, Bernardi et al . ([1985][1]) defined three major classes of genomic fragments with low, median, and high GC content, respectively, and called them isochores. This discrete description now
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