Hormonal, pituitary magnetic resonance, <i>LHX4</i> and <i>HESX1</i> evaluation in patients with hypopituitarism and ectopic posterior pituitary lobe

Abstract

ACTH deficiency is frequent in patients with hypopituitarism and NPS (85%), the location of EPL at the median eminence was not predictive of the hormonal profile [isolated GH deficiency (IGHD) or CPHD], and LHX4 and HESX1 genes mutations remain rare causes of hypopituitarism associated with EPL.