Low Molecular Weight Heparin Improves Peritoneal Ultrafiltration and Blocks Complement and Coagulation

Abstract

The acute inflammatory reaction to PD fluid involves the complement and coagulation cascades. Addition of LMWH to the PD fluid improves ultrafiltration, inhibits formation of thrombin, and potentially blocks C5a activity. The present results motivate further investigations of the IP cascade systems in PD.