Genetic Variation in <i>PPARG</i> Encoding Peroxisome Proliferator-Activated Receptor γ Associated With Carotid Atherosclerosis

Abstract

The findings show an association between PPARG genotypes and carotid arterial phenotypes, and further reflect the prevailing view that the PPARG A12 allele protects against deleterious phenotypes. Also, whereas IMT and TPV are somewhat correlated with each other, they might also represent distinct traits with discrete determinants representing different stages of atherogenesis.