Maintenance Treatment of Schizophrenia With Risperidone or Haloperidol: 2-Year Outcomes

Abstract

When compared with patients given a low dose of haloperidol, risperidone-treated patients experienced similar improvements in positive and negative symptoms and similar risks of psychotic exacerbations. However, risperidone-treated patients appeared to feel subjectively better, as indicated by less anxiety and depression and fewer extrapyramidal side effects.