Publication | Closed Access
Molecular iodine as a versatile reagent for Hantzsch synthesis of 2-aminothiazole derivatives
17
Citations
30
References
2009
Year
Hantzsch SynthesisEngineeringFacile Synthesis2-Aminothiazolesmolecular IodinebromoketonesthioureaMolecular IodineOrganic ChemistryVersatile ReagentChemistryHeterocycle ChemistryAsymmetric CatalysisDerivative (Chemistry)Synthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
Abstract A simple and facile synthesis of 2-aminothiazoles has been accomplished using molecular iodine catalyzed condensation of bromoketones with thiourea. The advantage of this method is that pure products are formed very rapidly under mild conditions. Keywords: 2-aminothiazolesmolecular iodinebromoketonesthiourea
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