A Three‐Component Palladium‐Catalyzed Oxidative CC Coupling Reaction: A Domino Process in Two Dimensions

Abstract

Easy as ABC…︁ or CBA! Indoles can be selectively functionalized twice by a catalytic oxidative three-component coupling of arylboronates and β-ketoesters. The difference in the rates (see scheme) of the competing processes are amplified under the conditions of the three-component reaction. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.