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Relationships between the biological effects and chemical structure of the genotoxic mycotoxin, botryodiplodin
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1982
Year
Bioorganic ChemistryToxinologyMycotoxinsTransient AldehydeRedox BiologyToxicological MechanismOxidative StressHemiacetal StructureMycotoxin FormationBioanalysisToxicologyHealth SciencesBiological EffectsBiochemistryMycotoxin BotryodiplodinMycotoxicologyPharmacologyGenotoxic MycotoxinMedicine
The mycotoxin botryodiplodin possesses various biological properties (genotoxicity and action on cell metabolism). It is demonstrated that the activity of the toxin is primarily due to the hemiacetal structure of the molecule, probably via the formation of a transient aldehyde.