<i>CCN3</i> Inhibits Neointimal Hyperplasia Through Modulation of Smooth Muscle Cell Growth and Migration

Abstract

CCN3 suppresses neointimal thickening through the inhibition of VSMC migration and proliferation. Our findings indicate the involvement of CCN3 in vascular homeostasis, especially on injury, and the potential usefulness of this molecule in the modulation of atherosclerotic vascular disease.