Effectiveness of topical caffeine in cataract prevention: studies with galactose cataract.

Abstract

Micromolar amounts of topical caffeine have been found to be significantly effective in inhibiting the formation of galactose cataract, strongly suggesting its possible usefulness against diabetic cataracts. The effects are attributed to its ability to prevent oxidative stress and consequent maintenance of tissue metabolic and transport functions, in addition to preventing the induction of apoptosis.