Granulocytic Sarcoma in a Patient With Blast Crisis Mimicking a Chronic Subdural Hematoma

Abstract

A 34-year-old black man was admitted to the neurosurgical intensive care unit with a 1-day history of progressive weakness and decreased mental status. He was known to the neurosurgical service, having presented 1 week prior for evaluation of persistent headaches for 1 month. At that time, he was diagnosed with bilateral chronic subdural hematomas and observed in the neurosurgical unit for 1 week, after which he left against medical advice. He had no history of head trauma, anticoagulation, or thrombocytopenia. His medical history was notable for chronic myelogenous leukemia (CML) diagnosed at our institution 10 months prior, for which he was receiving imatinib 600 mg daily. The patient had a known history of poor adherence to his leukemia management.