Concepedia

Induction of proline-rich tyrosine kinase 2 activation-mediated C6 glioma cell invasion after anti-vascular endothelial growth factor therapy

Chengshi Xu, Liming Dai, Sheng‐Hua Chu, Ling-Ling Gong, Minghuan Yang, Zhiqiang Li

Journal of Translational Medicine · 2014 · 18 citations · 25 references

DOIFull text

Open access

Abstract

These results suggest that anti-VEGF treatment promotes glioma cell invasion via activation of Pyk2. Inhibition of Pyk2 phosphorylation might be a potential target to ameliorate the therapeutic efficiency of anti-VEGF treatment.

References

25

Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group

Patrick Y. Wen, David R. Macdonald, David A. Reardon et al. · Journal of Clinical Oncology · 2010 · 3.7K citations · Full text

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A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

Mark R. Gilbert, James J. Dignam, Terri S. Armstrong et al. · New England Journal of Medicine · 2014 · 2.7K citations · Full text

Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma

Henry S. Friedman, Michael D. Prados, Patrick Y. Wen et al. · Journal of Clinical Oncology · 2009 · 2.4K citations

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

Marta Pàez‐Ribes, Elizabeth Allen, James Hudock et al. · Cancer Cell · 2009 · 2.3K citations · Full text

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Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

John M.L. Ebos, Christina R. Lee, William Cruz‐Muñoz et al. · Cancer Cell · 2009 · 1.7K citations · Full text

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