Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease

Abstract

YKL-40 and chitotriosidase are increased in asthma and more so in COPD. The data in the present study support these substances as being relatively steroid-insensitive, non-T-helper cell type 2-type biomarkers distinctly related to chronic inflammatory disease processes.