A Gly15Arg Mutation in the Interleukin-10 Gene Reduces Secretion of Interleukin-10 in Crohn Disease - Concepedia

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A Gly15Arg Mutation in the Interleukin-10 Gene Reduces Secretion of Interleukin-10 in Crohn Disease

27

Citations

16

References

2003

Year

van der Linde K, Patrick P.C. Boor, Lodewijk A. Sandkuijl, Maarten A.C. Meijssen, H. F. J. Savelkoul, J. H. P. Wilson, de Rooij F. W. M.

Scandinavian Journal of Gastroenterology

Abstract

A Gly15Arg mutation in the leader sequence of IL-10 was found in a multiple CD-affected family. This altered leader sequence decreases IL-10 secretion, thereby reducing the anti-inflammatory effect.

References

	Year	Citations

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