Comparison of bone morphogenetic protein‐2 delivery systems to induce supracrestal bone guided by titanium implants in the rabbit mandible

Abstract

The use of an implant system composed of a partially inserted Ti implant, adjacent scaffold and scaffold stabilizer resulted in the formation of new supracrestal bone across all test groups with and without BMP-2. Delivery of BMP-2 directly from the Ti implant increased bone height, BIC and bone volume as compared to no BMP-2 when a Col/HA was used, but did not improve performance of the HA/β-TCP/PEG scaffold.