Intrathecal neostigmine with bupivacaine for infants undergoing lower abdominal and urogenital procedures: dose response

Abstract

IT neostigmine at a dose of 0.75 microg/kg added to bupivacaine significantly prolonged SA duration with reduced postoperative pain scores and rescue analgesic requirements in infants undergoing lower abdominal and urogenital procedures. No additional benefits were provided on increasing it to 1 microg/kg.