Increased Progesterone Production During the Luteal Phase of Menstruation May Decrease Anesthetic Requirement

Abstract

The aim of this study was to determine the effect of high progesterone levels on anesthetic requirement. We measured progesterone levels before surgery and calculated the sevoflurane dose (MAC-h) required to maintain a constant bispectral index value. The dose of sevoflurane correlated inversely with serum progesterone concentrations.