Evaluation of Circulating Endothelial and Platelet Microparticles in Men with Ankylosing Spondylitis

Abstract

Circulating EMP and PMP, known to be indicators and mediators of vascular injury, were not significantly altered in men with AS who did not have classical cardiovascular risk factors. Significantly downregulated MP in patients receiving biological agents suggested that anti-TNF treatment may have a beneficial effect on vascular function in AS.